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  1. Basics of CPB cannulation
  2. Myocardial protection in cardiac surgery
  3. Introduction
  4. Myocardial protection: an overview.
  5. Myocardial Protection of Exenatide in AMI (EMPIRE)

The history of heart and heart-lung transplantation. Cardiovasc Clin ; The registry of the international society for heart and lung transplantation: twenty-seventh official adult heart transplant report J Heart Lung Transplant ; United Network of Organ Sharing data, to J Am Coll Cardiol ; Early donor management increases the retrieval rate of hearts for transplantation in marginal donors. Eur J Cardiothorac Surg ;; discussion A further contribution regarding the influence of the different constituents of the blood on the contraction of the heart. J Physiol ; The mechanism of myocardial damage following potassium citrate Melrose cardioplegia.

Perspectives in organ preservation. Transplantation ; New solutions in organ preservation.

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Topical cardiac hypothermia for extended periods of anoxic arrest. Surg Forum ; The mechanism of paraplegia after temporary thoracic aortic occlusion and its relationship to spinal fluid pressure. Direct coronary artery perfusion for aortic valve surgery; report of technique. J Am Med Assoc ; Ventricular fibrillation during hypothermia, used as a method to facilitate intracardiac operations. Acta Chir Scand ; Myocardial resistance and tolerance to ischemia: physiological and biochemical basis. J Cardiovasc Surg Torino ; Cellular protection during myocardial ischemia: the development and characterization of a procedure for the induction of reversible ischaemic arrest.

Basics of CPB cannulation

Circulation ; Recent progress in myocardial protection during cardiac operations. Ultrastructural damage associated with reoxygenation of the anoxic myocardium. J Mol Cell Cardiol ; Cardioplegia and cardiac surgery: pharmacological arrest and cardioprotection during global ischemia and reperfusion. Pharmacol Ther ; Myocardial preservation using HTK solution for heart transplantation. A multicenter study. Eur J Cardiothorac Surg ; Myocardial protection in donor heart preservation: a comparison between Bretschneider's histidine-tryptophan-ketoglutarate solution and cold blood cardioplegia.

Transplant Proc ; Creatine kinase and troponin after myocardial preservation using HTK solution Custoidol for clinical heart transplantation. Mannitol in cardioplegia as an oxygen free radical scavenger measured by malondialdehyde. Perfusion ; Milestones in the development of cardioplegia. Ann Thorac Surg ; Clinical validation of St. Thomas' hospital cardioplegic solution No. Blood versus crystalloid cardioplegia for myocardial protection of donor hearts during transplantation: a prospective, randomized clinical trial.

J Thorac Cardiovasc Surg ; Myocardial protection in heart transplantation using blood cardioplegia: year outcome of a prospective randomized trial. Kidney preservation for transportation. Experimental analysis of optimal perfusate composition. Br J Surg ; Improving Euro-Collins flushing solution's ability to protect kidneys from normothermic ischemia. Miner Electrolyte Metab ; A comparison of intracellular solutions for donor heart preservation. Southard MDa, Folkert O.

  • An overview of different methods of myocardial protection currently employed peri-transplantation?
  • An overview of different methods of myocardial protection currently employed peri-transplantation.
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Belzer MD. Ann Rev Med ; Successful hour cold storage of dog kidneys with UW solution. Extended preservation of human liver grafts with UW solution. JAMA ; Preservation of the canine liver for hours using simple cold storage with UW solution. Preservation of mouse liver tissue during cold storage in experimental solutions assessed by x-ray microanalysis. Liver Transpl ; Effect of cold storage on tissue and cellular glutathione.

Cryobiology ; Evaluation of UW solution in rat kidney preservation. The effect of pharmacological additives. University of Wisconsin solution versus crystalloid cardioplegia for human donor heart preservation.

Myocardial protection in cardiac surgery

A randomized blinded prospective clinical trial. J Thorac Cardiovasc Surg ;; discussion Endothelial dysfunction caused by University of Wisconsin preservation solution in the rat heart. The importance of temperature. Heart preservation in HTK solution: role of coronary vasculature in recovery of cardiac function. High-risk heart grafts: effective preservation with Celsior solution. Heart Vessels ; Clinical impact of histidine-ketoglutarate-tryptophan HTK cardioplegic solution on the perioperative period in open heart surgery patients.

Arch Med Res ; Combined St.

Thomas and histidine-tryptophan-ketoglutarat solutions for myocardial preservation in heart transplantation patients. A multicenter, randomized, controlled trial of Celsior for flush and hypothermic storage of cardiac allografts.

Pathophysiology of myocardial reperfusion

Improved graft function using a new myocardial preservation solution: Celsior. Preliminary data from a randomized prospective study.


Does the cardioplegic solution have an effect on early outcomes following heart transplantation? Eur J Cardiothorac Surg ;e; discussion e A novel method of measuring cardiac preservation injury demonstrates University of Wisconsin solution is associated with less ischaemic necrosis than Celsior in early cardiac allograft biopsy specimens. Organ storage with University of Wisconsin solution is associated with improved outcomes after orthotopic heart transplantation.

Long-term outcomes after heart transplantations in six different eras of innovation in a single center. Transpl Int ; Myocardial protection for transplantation. Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?

Myocardial protection: an overview.

Celsior versus custodiol: early postischemic recovery after cardioplegia and ischemia at 5 degrees C. The prognostic value of troponin release after adult cardiac surgery - a meta-analysis. Perioperative myocardial injury after adult heart transplant: determinants and prognostic value. PLoS One ;e Mechanisms of postischemic contractile dysfunction.

Biomarkers after heart transplantation: nongenomic. Heart Fail Clin ; Off-pump CABG attenuates myocardial enzyme leakage but not postoperative brain natriuretic peptide secretion. Ann Thorac Cardiovasc Surg ; Plasma brain natriuretic peptide and cardiac troponin I concentrations after adult cardiac surgery: association with cardiovascular death, postoperative cardiac, renal and pulmonary dysfunction.

Myocardial Protection: Fundamental Concepts

Brain natriuretic peptide BNP as a biomarker of myocardial ischemia-reperfusion injury in cardiac transplantation. J Cardiothorac Vasc Anesth ; MicroRNAs in coronary heart disease: ready to enter the clinical arena? Biomed Res Int ; Circulating miRNAs reflect early myocardial injury and recovery after heart transplantation.

Myocardial Protection of Exenatide in AMI (EMPIRE)

J Cardiothorac Surg ; The effect of ischaemic time on survival after heart transplantation varies by donor age: an analysis of the United Network for organ sharing database. Life-years gained by reducing donor heart ischaemic times. Continuous perfusion of donor hearts in the beating state extends preservation time and improves recovery of function.

Normothermic donor heart perfusion: current clinical experience and the future. J Heart Lung Transplant ;S Lancet ; Nonheart-beating donors: the Maastricht experience.

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  • An overview of different methods of myocardial protection currently employed peri-transplantation.
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  • Principles and Practice: Myocardial preservation.

Clin Transpl Normothermic ex vivo perfusion provides superior organ preservation and enables viability assessment of hearts from DCD donors. Am J Transplant ; Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series. Pediatric heart transplantation after declaration of cardiocirculatory death. N Engl J Med ; Walsh F. Europe's first non-beating heart transplant. The dead-donor rule and the future of organ donation.

Cardiac organ donor management. Myocardial function at the early phase of traumatic brain injury: a prospective controlled study.